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Self-Bind™ – Peptide
Microarray Services
Zephyr ProteomiX provides its unique Self-Bind™ peptide microarray services to generate customized low-to-high content peptide microarrays. The Self-Bind™ peptide microarray combines Zephyr's CelluloSlideTM with the versatile properties of the Zephyrin molecule. The technology provides two different approaches for construction of a peptide microarray.
The chemical version of the Self-Bind™ peptide microarray is based on oriented conjugation of peptides to the Zephyrin™ carrier molecule. This version allows simple yet oriented immobilization of peptides that are routinely synthesized chemically with a cysteine residue at their C- or N-terminus. The recombinant version of the Self-Bind™ peptide microarray involves fusion of the desired peptide to Zephyrin™ and its expression in an E. coli host cell system. The recombinant purified Zephyrin-fused peptide is used for peptide microarray production. In addition, our recombinant version enables production of constrained and structural peptide microarrays. In both versions of the Self-Bind™ peptide microarray, multiple copies of peptide microarrays can be prepared at unmatched prices and turnaround rates.
Self-Bind™ Peptide
Microarray Applications:
- peptide mapping
- protein interactions
- epitope mapping
- identification of kinase substrates profiling of kinase substrate specificities
- identification of protease substrates and profiling of protease substrate specificities
- In-vitro diagnostic applications of serum, urine etc.
Key
Selling points:
- Unique system which provides immobilization of peptides in an oriented manner
- High binding capacity
- Highly sensitivity which enables quantitative measurements of various antigens
- Significant saving of cost and reagents
- Enables immobilization of constrained or structural peptides
- The recombinant version provides ultra-pure peptides (>95%).
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Self-Bind™ – antibody
microarray services
Zephyr proteomiX provides its unique Self-Bind™ antibody microarray platform to generate customized low-to-high content antibody microarrays. The Self-Bind™ antibody microarray combining Zephyr's CelluloSlide™ with the versatile properties of the Zephyrin-mSPA. The Self-Bind™ antibody microarray platform is the only commercial technology that enables oriented immobilization of antibodies. All we need for production of a custom antibody microarray is your panel of antibodies. Zephyr will produce multiple copies of the custom antibody at unmatched prices and turnaround times.
Self-Bind™ antibody microarray applications:
- Protein profiling in various biological samples
- Multiple quantification of proteins.
Key Selling points:
- Unique system which provides oriented manner antibody immobilization
- High binding capacity
- Highly sensitive assay which enables quantitative measurement of various antigens
- Significant savings of cost and reagents.
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request
Self-Bind™ – small-molecule
microarray services
Zephyr ProteomiX provides its unique self-bind™ small molecule microarray platform to generate customized low-to-high content small molecule microarray. The Self-Bind™ small-molecule microarray combing Zephyr's CelluloSlide™ with the versatile properties of the Zephyrin molecule. The technology is based on versatile chemical conjugation of the small molecule to a chemically activated form of the Zephyrin™ molecule. This technology provides oriented and controllable immobilization of the desired small-molecule to our carrier molecule - Zephyrin™. Small-molecules (such as carbohydrates, hormones, etc.) with accessible amine, hydroxyl or thiol (sulphydryl group) groups can be easily immobilized on the CelluloSlide™ via the Zephyrin™ molecule. The Self-Bind™ enables the production of multiple copies of small-molecule microarrays at unmatched prices and turnaround times.
Self-Bind™ small-molecule microarray applications:
- Mapping small molecule-protein interactions
- Enzyme-inhibitor or enzyme-substrate identification
- Mapping small molecule-cell/bacteria interaction
- In-vitro diagnostic applications of serum, urine etc.
Key Selling points:
- Unique system which provides oriented manner of immobilization of the small molecule
- High binding capacity
- Highly sensitive assay which enables quantitative measurement of various antigens
- Significant savings of cost and reagents
- Dual immobilization of small molecule and peptide.
Quote
request
High Throughput screening services
Zephyr ProteomiX has developed a novel method for HTS for hybridoma samples, for expression libraries of recombinant peptides/proteins and for screening of small molecule libraries. Please contact our Contract Research Division to discuss your project needs and for further information.
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